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In this regard, activation of PKC leads to a downstream activation of ERK1/2 which provides an additional and indirect level of zinc-mediated regulation of ERK1/2 [131] Zinc and tubulin thiols: regulation of NF-3B and NFAT nuclear transport A role for zinc in the regulation of cell signaling is also related to the preservation of tubulin polymerization dynamics through the maintenance of an adequate intracellular thiol redox status
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