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The best characterized TCR pathway is TC-NER, where stalling of RNA polymerase II by transcription-blocking DNA lesions triggers the excision of the damage from the transcribed strand mediated by XPA and the nucleases XPF-ERCC1 and XPG
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We tend to take adenosyl and/or hydroxy B12 (also called adenosylcobalamin or hydroxycobalamin)
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