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The postganglionic fibers of the sympathetic nerve are adrenergic nerve fibers which cause the release of norepinephrine that elicit the presynaptic inhibition of neurotransmitter release, thereby inhibiting intestinal motility
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To develop cardiac insulin resistance, major factors such as hyperglycemia, hyperlipidemia, oxidative stress, inappropriate activation of sympathetic nervous system and the renin-angiotensin II-aldosterone system (RAAS), and dysregulated secretion of adipokines/cytokines are all significant contributors [139]
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