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Thus, activation of NFΞΊB by ROS (or other signaling pathways) upregulates the expression and activity of ROS generators, such as NADPH oxidase 1 and 2 (NOX1 and NOX2) that produce superoxide [9, 10]
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As expected, BSO treatment effectively decreased levels of glutathione and Ξ³-Glu-Ser-Gly in both of 293T and iBMDM cells (Fig
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