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In turn, this disrupts the gut barrier function and may result in acute and chronic inflammatory states ( In addition, it is worth mentioning the so-called gut-vascular barrier (GVB), which is formed by endothelial cells surrounded by enteric glial cells and pericytes
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Instead, it is positioned closer to the outer side of the pocket, forming hydrogen bonds with several residues in the L2, L3, and L4 regions and being trapped at the pocket entrance
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