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g6pd deficiency and glutathione • Glucose-6-phosphate dehydrogenase deficiency • X-linked recessive disorder • Leads to low NADPH, impairing regeneration → RBCs are vulnerable to oxidative damage ⸻ Pathophysiology: In G6PD deficiency: • No HARDENING
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Ferroptosis is closely related to spontaneous preterm birth, and PLA2G6 can alleviate ferroptosis caused by GPX4 inhibition during pregnancy in mice (128)
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To assess relationships between patient age, mean daily isotretinoin dose, cumulative isotretinoin dose and the occurrence of specific adverse events, a Spearman rank correlation test was used as a non-parametric method for evaluating the strength and direction of monotonic associations between variables
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