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Glutathione Identified as Crucial Antioxidant for Accurate Protein Folding

The best-known red blood cell intrinsic mechanism of adaptation is an increase in bisphosphoglycerate (2,3-DPG) that shifts the Hb-O 2 dissociation curve to the right: this can be expected if the flow of glycolysis is impaired downstream, but not upstream, of the Rapoport-Luebering cycle (Figure 1)

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Inhibiting factor Xa decreases the conversion of prothrombin to thrombin