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Selon une analyse des données disponibles autour de 2015 dans la base de données Cochrane Database of Systematic Reviews, en cas de carence, la vitamine B 12 peut être délivrée par voie orale (elle est alors absorbée dans la partie terminale de l'iléon) ou par injection intramusculaire [79] , [80]
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The presence of diabetes and hyperglycemia tends to shift monocytes towards a functionally proinflammatory phenotype, which induces chronic inflammation and insufficient M2 functional profibrotic TGF-β signaling [29] similar to that seen in G6PD-deficient subjects
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