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Benign Prostatic Hyperplasia (BPH) | Chin Chong Min Urology & Robotic Surgery Centre
This protective effect is achieved through the upregulation of FPN1 expression, which reduces intracellular iron content, attenuates ROS production, and inhibits apoptosis (evidenced by reduced caspase-3 activation and DNA fragmentation) (53)
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Thus patients who have taken alcohol or these drugs are particularly susceptible to the toxic effects of paracetamol
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