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Additionally, circulating autoantibodies could affect the brain and autonomic nervous system due to an MC-induced hyperpermeable BBB and/or an abnormally functioning blood–cerebrospinal fluid barrier [8,29]
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The ICS-localized or peripheral intermembrane space-localized PKA IMS might phosphorylate the Complex IV COXIV-1 subunit, which prevents its inhibition by ATP and hence enhances respiration and OXPHOS (39)
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