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6.3 Limitations of novel delivery systems Although recent studies have reported substantial improvements in the delivery efficiency and therapeutic performance of flavonoids using advanced delivery systems, including enhanced stability, bioavailability, and targeting efficiency (Delgado-Pujol et al., 2025), several practical and clinical limitations have been identified, which merit further investigation and refinement
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The first Article 13 claim based on newly developed evidence or proprietary data (a particular category under Article 13(5)) was approved for Fruitflow ® in 2009 [30]
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