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Of these only 20% were heterozygous for the H63D mutation in the hemochromatosis gene, while the C282Y mutation was not detected, suggesting that iron overload rather than typical hemochromatosis mutations was associated with epilepsy development [69]

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Cette absence de preuve d'efficacité s'accompagne de signalements d'effets indésirables graves rapportés dans la littérature médicale et par les agences sanitaires : hépatotoxicité, insuffisance rénale, syndrome de Stevens-Johnson et réactions anaphylactiques