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After the plasma membrane carrier-mediated GSH release from the cell, GSH becomes accessible to the active site of γ - glutamyl transpeptidase, which catalyzes the breakdown of the GSH γ - glutamyl bond forming two fractions: The γ-glutamyl fraction and the cysteinyl-glycine by transferring the γ-glutamyl fraction to an amino acid acceptor, forming γ-glutamyl-amino acid
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Expectedly, UNC10088 C interactions with NSD2 are similar to those with the NSD2 chemical probe (UNC6934) (Supplementary Fig
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