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Mitochondria are major sources of free radicals, and in addition to being commonly used to treat disoriented circadian clocks due to jet lag and other disturbances (i.e., sleep inefficiency) 18 , melatonin has been widely used as an antioxidative therapy 19 and its use dates back to 1993 (refs
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The company’s revenue and gross profit mix is also intentionally diversified: branded therapies represent roughly ~50% of revenue but less than 20% of gross profit, while no single therapy represents more than 4% of company gross profit, underscoring the resilience of the portfolio despite periodic drug-specific reimbursement or biosimilar headwinds
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