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Doxycycline prevents and reverses schizophrenic-like behaviors induced by ketamine in mice via modulation of oxidative, nitrergic and cholinergic pathways - ScienceDirect
This process is a key step in the mitochondria-dependent apoptosis pathway
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As a result, SAMe production is decreased, which, in turn, can lead to decreased glutathione synthesis since SAMe is required for the production of glutathione
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