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Semaglutide# Semaglutide is a synthetic GLP-1(7-37) analog with an Aib substitution at position 8 for DPP-4 resistance and a C18 fatty diacid chain at lysine-26 for albumin binding, giving it a half-life of approximately 7 days
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While the exact cause of melasma is not fully understood, hormonal changes , particularly increased levels of estrogen and progesterone, play a significant role
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