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Keywords: glutathione, redox signaling, glutathionylation, GSNO, nitrosylation Introduction Several reactive species derived from oxygen and nitrogen are produced in cells from a variety sources such as NADPH oxidases (NOX) [1], leaks from the mitochondrial electron transport chain [2], redox cycling of quinones [3], and nitric oxide synthases (NOS) [4]
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All dose arms met the primary endpoint
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