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Glucose-6-phosphate dehydrogenase deficiency - The Lancet
[DOI] [PMC free article] [PubMed] [Google Scholar] 3.Alaba, T
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Elevated iron levels observed in the PD substantia nigra further amplify ROS production through Fenton chemistry (Sian-HΓΌlsmann et al., 2011), creating a vicious cycle of oxidative stress and mitochondrial damage that ultimately promotes neuronal death through apoptosis, necrosis, or ferroptosis (Ayton and Lei, 2014)
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