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The problem with remdesivir Remdesivir is currently the only antiviral drug approved for use against SARS-CoV-2, while another compound called molnupiravir is also emerging as a potential candidate
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The chain runs in order: NNMT inhibition, then reduced SAM consumption and reduced MNA output, then nicotinamide retained for NAD+ salvage, then altered NAD+/NADH balance and downstream sirtuin signalling
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