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Manipulating CSE and ETHE1 levels in both directions, we found a consistent pattern in that the two enzymes mirrored each other: silencing CSE yielded the same effect (slower radical removal) as overexpressing ETHE1, and overexpressing CSE yielded the same effect (faster radical removal) as silencing ETHE1 (Fig
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Remarkably, some tumor cell lines such as MCF-7 and T47D have shown drug resistance to statins due to a feedback response triggered by HMGCR activation ( Traditional Chinese Medicine (TCM) has been extensively used in East Asia for cancer treatment, either as a standalone approach or as a complementary therapy
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