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What is more, TNF-alpha is reported to be involved in the skin-aging process, and chronic inflammation, which it mediates, is believed to be responsible for the formation of wrinkles and other signs such as poor hydration or the disintegration of dermis and epidermis junctions 40
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Acetaldehyde is further metabolized to acetate by aldehyde dehydrogenase (ALDH) and ultimately broken down into carbon dioxide and water for excretion (Yang et al ., 2022)
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