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They then noticed that the pineal gland changed with age and made a conclusion that it might contain and produce substances regulating aging
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Further, melatonin has been shown to decrease nocturnal hypertension, improve systolic and diastolic blood pressure, reduce the pulsatility index in the internal carotid artery, decrease platelet aggregation, and reduce serum catecholamine levels [120,121,122,123]
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