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In a German RCT of healthy lactating women from high-income countries, use of MMS (containing 500 μg folic acid plus 200 mg DHA and 250 μg lutein) during the lactation period led to significant increases in maternal milk levels of DHA, EPA, and beta-carotene, and maternal blood levels of DHA, EPA, 25(OH)D, folate, vitamin B12, lutein, and beta-carotene—all of which decreased with placebo

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Quinazolines Alongside classical phthalazin-1(2H)-one cores, PARP inhibitor design increasingly explores alternative rigid heteroaromatic scaffolds, particularly 4(3H)-quinazolinones and quinoxaline frameworks, as NAD+-competitive chemotypes that can preserve the key hydrogen-bonding pattern within the nicotinamide-binding pocket of PARP-1/2 [171,172,173]