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The engineered bacteria were subject to periodic lysis inside tumors, releasing LIGHT, which bound to host HVEM receptors and promoted the development of mature tertiary lymphoid structures (mTLSs)
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To further elucidate how these adipocytes affect fatty acid oxidation in tumor cells, we treated Mock and MST6-I gastric cancer cells with the secretome from white or beige-like adipocytes [TWAT(Mock) and TWAT(MST6-I)] [Figure 4A] and performed a Seahorse analysis
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