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Given that an increase, but not a decrease, in the Kyn/Trp ratio is expected to be associated with inflammation, and that we observe a one-directional trend towards increased values among the asymptomatic V30M carriers compared to controls (Table 2

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Ultrasound can also be a useful modality for looking for extraintestinal disease (Figure 6) but like any other diagnostic test, it is most effective when it follows clinical judgment – an ultrasound exam should not be a “fishing trip”