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AO epigallocatechin-3-gallate, a most abundant catechin in green tea, reduces gingival inflammation, prevent bone resorption and limit the growth of periodontal pathogens, thus promoting periodontal health.[138] Organosulfur-compound diallyl sulfide enhances AO activities by scavenging superoxide ions and enhancing GSHPX levels, thus unveiling a significant antimicrobial effect against the Aggregatibacter actinomycetemcomitans .[139] Recent reports suggest that the topical use of esterified glutathione could potentially minimize effects of OS with raised intracellular levels of glutathione and acceleration of wound healing by improving the capacity of fibroblasts and keratinocytes.[88] Oxidative stress is one of the underlying factors explaining the systemic pathophysiological mechanisms associated with the chronic inflammatory conditions as periodontitis.[99] A decrease in salivary reduced-glutathione levels in type 1 diabetes mellitus patients may have a role in the destruction of the periodontium by predisposing the periodontal tissues to OS.[70] It can be postulated that patients with reduced or depleted glutathione content, as in systemic disorders with compromised AO defenses,[82] may be more prone to further increase in OS, and worsening of the condition when superimposed with periodontal infection Size:3 Months Supply (Recommended) แบรนด์ exxe https://5.imimg.com/data5/SELLER/Default/2024/5/420265308/WL/TH/YM/35761403/authentic-ishigaki-plus-premium-glutathione-850mg-250x250.jpeg BOTO] BỘT TRUYỀN TRẮNG GLUTATHIONE COLLAGEN, Collagen Phân Tử C Biotin 4g x 30 Gói, Làm Trắng Da | Shopee Việt Nam Neutraceuticals